Publications

Take a closer look to all publications authored by the Lewis Lab to gain deeper insights into our research and contribution

Recent Publications

Sophisticated natural products as antibiotics

Nature

A new antibiotic selectively kills Gram-negative pathogens

Nature

The Science of Antibiotic Discovery

Cell

Stochastic Variation in Expression of the Tricarboxylic Acid Cycle Produces Persister Cells

mBio

Computational identification of a systemic antibiotic for Gram-negative bacteria

Nature Microbiology

The Role of Integration Host Factor in Escherichia coli Persister Formation

mBio

Evybactin is a DNA gyrase inhibitor that selectively kills Mycobacterium tuberculosis

Nature Chemical Biology

Teixobactin kills bacteria by a two-pronged attack on the cell envelope

Nature

A Selective Antibiotic for Lyme Disease

Cell

Bacterial persisters are a stochastically formed subpopulation of low-energy cells

PLoS Biology

The antibiotic darobactin mimics a β-strand to inhibit outer membrane insertase

Nature

A Distinct Microbiome Signature in Posttreatment Lyme Disease Patients

mBio

Novel Antimicrobials from Uncultured Bacteria Acting against Mycobacterium tuberculosis

mBio

GABA-modulating bacteria of the human gut microbiota

Nature Microbiology

Identifying Vancomycin as an effective antibiotic for killing Borrelia Burgdorferi

Antimicrob Agents Chemother

A genetic determinant of persister cell formation in bacterial pathogens

J Bacteriol

ATP dependent persister formation in Escherichia coli

mBio

Persister formation in Staphylococcus aureus is associated with ATP depletion